Besieged e-health company iSOFT has confirmed the departure of former chief executive Gary Cohen, just weeks after he quietly resigned from the CEO role in late August.

The long-time chief executive of troubled e-health giant iSOFT, Gary Cohen, has resigned. His departure was revealed as part of the company's annual financial results for the year to 30 June; revenues were down 20 per cent to $431 million over the previous year, and earnings before interest, depreciation and taxation down 77 per cent to $30 million. iSOFT has commenced an in-depth review into its operations as a result.