Focusing on your interests and strengths the way McGoldrick did will help you more easily recognize opportunities as they come along and determine whether they're a good fit for you.

4. Try your possibilities on for size: What would this new career really be like?

Technical graphic designer Marissa Rosenfield Smajlaj was shopping at a bookstore in downtown Boston when she came upon a copy of the book Colette's Birthday Cakes by world-renowned specialty cake artist Collette Peters. As she flipped through the pages and admired each cake, she had an epiphany: "I could do this!" she thought. Smajlaj got a part-time job in a bakery to see if she'd enjoy the work. She loved it, decided to go to culinary school and was accepted at the prestigious Le Cordon Bleu in London. She completed the Le Cordon Bleu Diplome de Patisserie. The following year, she became a pastry chef at a New York City restaurant. She hasn't looked back since.

5. Be open to opportunities: What's out there?

Bill Sobbing didn't start out as an IT professional. In college, he majored in English. When he graduated, he didn't know what he wanted to do with his life. He looked at many different possibilities, but none of them excited him. Eventually, a relative got him a job where the relative was working. When the IT department at Sobbing's company posted an entry-level position, he applied for it and was accepted. Sobbing found a career that interested him and spent the next 20 years working in various IT roles. He enjoyed the work but, like many IT managers, he tired of corporate politics. He decided to become an independent consultant and began working primarily from his home. One morning, he picked up a newspaper and read about a local school, which offered a program in golf course management. He had played golf casually since high school but never considered making it his career. Yet something in the story about the golf academy compelled him to check it out. Three years later, Sobbing is general manager of a nine-hole golf course. He could never have done it if he hadn't indulged his curiosity.

6. Select the right opportunities: Which are viable?

In 2002, Alan Klug was a senior consultant with KPMG. He enjoyed working with clients, but the consulting industry was suffering from the post-9/11 economic recession at that time. Klug knew future consulting opportunities would be limited and decided to pursue something entrepreneurial. He considered opening a custom closets business, a car wash, and franchising a quick-service restaurant. He developed business plans for each idea, but none of them really grabbed him. Then he came across a small ad in Fortune for 1-800-GOT-JUNK? Intrigued by a company that got paid for taking people's junk off their hands, he says he "researched the heck out of it." He learned that it was a lucrative and fast-growing business with a solid strategy and good management team heading it up. In 2003, he became a 1-800-GOT-JUNK? franchisee with four territories. He has since expanded to eight territories. He is on track to become a US$2 million business in 2008 and is already thinking about what he might do next. "If an opportunity comes along, don't count it out immediately because it seems too good to be true. Just research it and find all the downsides," he says. "There are plenty of opportunities out there to be exploited."